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JWH-018 is a type of analgesic chemical from your naphthoylindole spouse and children that capabilities as a complete agonist at both the CB1 and CB2 cannabinoid receptors. It was 1st synthesized by Dr. John W. Huffman and is discovered in herbal smoking blends like Spice. The analgesic effects of cannabinoid ligands, that happen to be mediated by